10 Most Popular Medical Billing Software for Small Business

Medical billing software simplifies the healthcare billing process for doctors and medical offices by automating it. Finding suitable software can enhance your office’s reimbursement rates, optimize revenues, and support a sustainable medical practice.

Assess your office’s needs to choose the best medical billing software. Look for software that manages appointment scheduling, automatically enters patient data during consultations, and includes scrubbing features to boost insurance company acceptance rates. The top programs provide comprehensive practice health reports and analytics. TECHVIFY has reviewed the leading medical billing software for Small Businesses to help you select the most suitable one.

I. Medical Billing Software for Small Businesses

1. DrChrono 

DrChrono is a cloud-based billing software and patient management portal designed to handle various medical billing tasks efficiently. It allows office staff to access patient information online or through an iPad/iPhone app. The system handles patient intake, care, clinical charting, and billing.

Intake nurses can enter patient vital data, while doctors can add notes from patient visits. The Electronic Prescribing Controlled Substances feature enables doctors to prescribe controlled substances efficiently while staying compliant. The system also facilitates ordering lab tests from 45,000 U.S. labs for accurate and convenient health details and results.

medical billing software for small business


Doctors can annotate records and use an iPad to add photos directly to patient files. Billing codes are pre-populated for easier processing. DrChrono integrates with Box for HIPAA-compliant cloud storage and several partner apps.

Target-users: Suitable for medical providers of any size and billing offices, DrChrono simplifies patient management tasks.


  • Practice-based pricing
  • Record annotation
  • Integrates with various partner apps


  • No phone support, only e-tickets
  • Limited search and navigation features

2. CureMD 

CureMD is one of the best small business billing software for billing, electronic health records management, and patient portals. Patients can log in to view their records. The service operates on subscription packages and includes site hosting, training, and security to help practices maximize the system’s benefits.

CureMD integrates with thousands of pharmacies and labs, allowing doctors to easily order medications and tests for patients. The extensive network also enables patients to obtain their prescriptions and tests at home or work.

medical billing software for small business


An iPad app simplifies patient intake and appointment notes, while insurance claims settlement features automate billing, reducing paperwork for providers.

Target-users: CureMD is suitable for large practices seeking to automate functions to focus more on patient care.


  • iPad app simplifies tasks
  • Advanced Reporting
  • Wide network of pharmacies and labs


  • Implementation can be confusing
  • Browser version only compatible with Internet Explorer

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3. CentralReach 

CentralReach is a medical billing software and practice management system tailored to Applied Behavior Analysis (ABA) therapies. It is ideal for practitioners treating autism and related cognitive disorders.

The integrated medical billing systems software functionality provides claim scrubbing to process claims quickly and minimize payment issues, enhancing system reliability. The built-in clearinghouse improves efficiency by streamlining claims processing for office staff. The system identifies secondary and tertiary insurance providers, ensuring that all payment options are utilized and helping patients make the most of their benefits.

medical billing software for small business


CentralReach’s mobile app allows clinicians to input data in real-time. The software includes customizable templates that simplify clinical documentation and pre-filling provider, client, and billing information. It is HIPAA and PCI-compliant.

Target-users: Behavioral therapists specializing in ABA therapies, whether in individual practice or working within the education system.


  • Free trial available
  • Efficient secondary insurance billing
  • Customizable templates


  • Delayed reporting can affect data accuracy
  • System freezing may lead to lost notes

4. Kareo Billing

Kareo Billing is a web-based patient management system offering medical billing and patient data functions. It automates many features, ensuring that when practitioners input patient data, billing codes immediately handle insurance processing.

Kareo Billing also manages patient care with its integrated schedule, sending appointment reminders to minimize no-shows. This allows practitioners to schedule annual appointments as needed.

medical billing software for small business

Kareo Billing

Practitioners will benefit from Kareo’s business management features like billing analytics, document management, and an agenda planner. The software is ICD-10 compliant, meeting requirements for services provided on or after October 1, 2015.

Target-users: Small practices with low transaction volumes can benefit from the per-claim billing structure.


  • Easy to use
  • Comprehensive analytics
  • Immediate processing


  • Scheduling incurs a fee
  • Subpar customer support and training

5. AdvancedMD 

AdvancedMD is a cloud-based patient management system hosted on the Amazon Web Services (AWS) platform, ensuring speed and reliability for busy medical professionals. It provides secure online and iPad data access and follows ISO 27001 standards for comprehensive risk management.

With AdvancedMD, medical practices can handle appointment scheduling, patient records, billing, and relationship management. Automated processes and intuitive dashboards streamline workflows, and analytics provide a clear overview.

medical billing software for small business


The patient portal allows for real-time feedback, improving services and patient retention. Specialty cards organize data for faster, more personalized patient interactions.

Target-users: Ideal users include providers prioritizing personalized care and empowering patients to manage their health.


  • Secured iPad function
  • Fast system performance
  • Comprehensive patient portal


  • Negative user reviews
  • Poor customer service reports

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6. CollaborateMD 

CollaborateMD is appreciated for its low cost and ease of use. The clean, simple interface is user-friendly, even for those new to this type of software. It integrates with all EHRs, and the company guarantees that integrations will be created for any unsupported EHRs used by your practice.

Beyond billing, CollaborateMD’s practice management features include easy appointment scheduling, quick patient eligibility assessments for insurance verification, and comprehensive financial reports to monitor your practice’s financial performance.

medical billing software for small business


Target-users: CollaborateMD is suitable for small to mid-sized medical practices that need cost-effective billing software with integrated practice management features.


  • Multiple payment plans
  • Easy appointment scheduling
  • EHR integration


  • Full suite not available in lower tiers
  • Limited cloud storage in most plans

7. Dentrix 

Dentrix streamlines dental practice management, automating invoicing, payment collection, processing, and claims management. Ideal for dental and orthodontic practices of all sizes, it simplifies billing with real-time eligibility assessment and diverse payment options. Additionally, Dentrix assists with business management, tech support, marketing, and promotions.

medical billing software for small business


Target-users: Dentrix is suitable for dental practices of all sizes, including dentists, orthodontists, and other oral healthcare providers seeking to automate and improve their billing, patient management, and overall practice operations


  • Efficient patient information management
  • Claims management assistance
  • Electronic prescription handling


  • Inadequate technical support
  • Slow software

8. Alora Home Health’s

Providing healthcare to patients at home or in mobile settings like clinics, workplaces, and shelters poses unique challenges, particularly with managing payments. Alora Home Health’s billing software can help streamline payment processing for teams away from the office, reducing the risk of lost payments. It integrates with Medicare, Medicaid, VA, and private insurers, automating billing, tracking claims, and managing reimbursements.

medical billing software for small business


As a platform designed to support mobile and home healthcare providers, Alora works on various devices like desktop and laptop computers, tablets, and smartphones. This flexibility allows teams to manage billing, appointments, compliance, and more while on the go or back in the office.

Target-users: Alora Home Health’s billing software is ideal for healthcare providers who deliver services outside of traditional office settings:

  • Home healthcare agencies provide care directly at patients’ homes
  • Mobile clinics offering healthcare services in different locations
  • Workplace healthcare teams managing employee health programs
  • Clinics providing healthcare support in shelters or community facilities


  • Good customer support
  • Tiered pricing plans are available
  • Compatible with multiple devices


  • Missing some medications and allergy data in the database
  • Occasional software lags or crashes

9. athenaCollector

athenaCollector, part of the athenahealth suite, is a medical billing software designed to streamline billing processes for healthcare practices. It simplifies user experience and makes medical billing more efficient.

As a cloud-based solution, AthenaCollector provides real-time updates and access from any location. This allows users to access accurate billing data quickly and efficiently.

medical billing software for small business


Its intelligent billing rules engine relies on a network of over 160,000 healthcare providers. This engine continuously updates to align with new guidelines, reducing the chance of claim denials and speeding up reimbursements.

The application also provides tools for analytics and reporting. These tools provide practices with a clear view of their financial performance, enabling them to identify areas for improvement and optimize revenue collection. Visual dashboards and reports make data analysis straightforward.


  • Clinics, hospitals, and private practices want to improve their billing processes.
  • Organizations managing billing for multiple healthcare providers.
  • Facilities needing scalable, real-time billing management.


  • Real-time updates and data access from any location.
  • Reduces claim denials with frequently updated rules.
  • Offers clear insights into financial performance.
  • Suitable for practices of various sizes and complexity.


  • Pricing might be higher for smaller practices.
  • Cloud-based nature requires a stable internet connection.

10. NextGen 

NextGen Medical Billing Software for small practices is designed to improve billing operations. Part of NextGen Healthcare’s suite, it modernizes and simplifies billing for healthcare providers.

Key features include strong automation, reducing manual data entry, saving time, and minimizing errors that could delay reimbursements. The software captures billing information efficiently, speeding up the billing cycle and improving cash flow.

medical billing software for small business


The intuitive user interface ensures a quick learning process for staff, helping healthcare practices maintain efficiency.

NextGen also integrates with Electronic Health Records (EHR) systems, providing a single platform for clinical and administrative tasks. This integration improves coordination among staff and boosts the practice’s efficiency.


  • Clinics that rely on manual billing processes and want to reduce errors.
  • Practices seeking seamless integration between their billing and EHR systems.


  • Cuts down on manual data input, helping conserve time and reduce mistakes.
  • Connects seamlessly with EHR systems for unified clinical and administrative management.
  • Easy for staff to learn, reducing training time and maintaining operational efficiency.
  • Improves billing accuracy, resulting in quicker reimbursements and better cash flow.


  • Some practices may find the customization options limited compared to their unique needs.
  • While the interface is user-friendly, understanding all features may take time for some staff.

II. What you need to know before Buying Medical Billing Software

With many applications available, you may find it hard to decide. Consider following these steps to choose your best billing software for small business.

  1. Pricing and Cost Structure: Consider whether your practice can afford the software. Analyze your finances carefully, as the savings it brings may justify the cost. Ensure that payment terms are flexible and can be arranged to suit your budget.

  2. Integration with HER/EMR Systems: Your practice likely already has a large collection of electronic health records or electronic medical records. Check that the software integrates without any issues with these existing systems. If integration isn’t possible, you may need to explore other options.

  3. Patient Information Management: Accurate patient data collection is vital in healthcare, as is secure storage of this sensitive information. The software should also offer reliable and easy access to this data for healthcare providers. Before finalizing your decision, assess the software’s patient information management and storage capabilities.

  4. Customization and Template Options: Customized documents, invoices, spreadsheets, and templates are essential for efficient billing. Request demonstrations of the software’s template customization options to ensure they meet your expectations and billing requirements.

  5. Payment Processing Capabilities: Any suitable billing software should accept payments from insurers, companies, and patients. It should handle various payment methods, such as credit and debit cards and wire transfers.

  6. User-Friendly Interface: Software that is intuitive and easy to use will ensure greater accuracy and reliability. Confirm that the software you select is user-friendly and not overly complicated.

  7. Customer Support and Training: Before committing to medical billing software, test the customer support team. Reach out with questions and evaluate the thoroughness and quality of their answers. If they don’t provide satisfactory responses initially, you can expect similar experiences once you are a customer.

III. What about making the Perfect Medical Billing Software just for You

Sometimes, the above options still don’t meet your requirements, and you are looking for something more original and works only for your specific needs, then our service is what you are missing.

TECHVIFY is a top software development company specializing in creating custom medical billing solutions tailored to your needs. We understand the challenges of modern healthcare billing and offer comprehensive, efficient software to optimize your practice.

  • Automated Billing and Revenue Management: Streamline billing cycles with automated appointment scheduling, data entry, claim scrubbing, and insurance verification. Our software reduces administrative burdens and boosts claim acceptance rates.

  • Seamless Data Integration: Integrate with existing EHR/EMR systems for consistent data flow, reducing errors and improving billing and clinical coordination.

  • Actionable Analytics: Use comprehensive dashboards to gain insights into key performance metrics, identify improvement opportunities, and optimize revenue collection.

  • Secure and Compliant: Our software meets strict compliance standards, protecting patient data while providing intuitive access for authorized personnel.

  • Scalable and Customizable: Our solutions scale with your practice and offer customizable templates to meet unique billing needs.

  • Reliable Support: Our dedicated team provides training, troubleshooting, and implementation support to ensure your staff can use the software effectively.


Choosing the right medical billing software is vital for improving your practice’s revenue and efficiency. Look at your specific needs and pick software that handles scheduling, patient data, and reporting easily. Integration, user-friendly design, and customer support are key factors to consider.

Contact TECHVIFY, a trusted medical billing software consulting and services leader, for expert guidance on choosing the best solution. Our team will help you implement the perfect solution, tailored to your practice’s unique needs. Contact TECHVIFY today and elevate your medical billing process to the next level!

TECHVIFY – Global AI & Software Solutions Company

For MVPs and Market Leaders: TECHVIFY prioritizes results, not just deliverables. Reduce time to market & see ROI early with high-performing Teams & Software Solutions.

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